YUDAEV Nikolay Alekseevich

From Big Medical Encyclopedia

YUDAEV Nikolay Alekseevich (1913 — 1983) is the Soviet biochemist, the endocrinologist, the academician of AMH (1965). Member of the CPSU.

In 1940 ended biological f-t of MSU and it was accepted in a postgraduate study Ying-that morphology of Academy of Sciences of the USSR. In

1941 — 1946 served in ranks of the Soviet Army. From 1946 to

1949 there was the assistant to department of medical chemistry Moscow medical in-that a M3

of RSFSR (nowadays Ryazan medical in-t), and in 1949 — 1951 the senior research associate in the group headed by the academician S. E. Severin. In 1951 protected dokt. thesis; professor (1955). In 1951 — 1965 manager. laboratory of nervous and humoral control Ying-that biological and medical chemistry of the USSR Academy of Medical Sciences and at the same time the deputy director in-that on scientific work. In 1965 — 1983 the director Ying-that experimental endocrinology and chemistry of hormones of the USSR Academy of Medical Sciences. From 1978 to the last days lives the academician-secretary of Department of medicobiological sciences of the USSR Academy of Medical Sciences.

N. A. Yudayev is the author of St. 200 scientific works, including several monographs devoted to hl. obr. biochemistry of hormones and neyrogumo-ralny regulation fiziol. functions of an organism. Its long-term researches of biosynthesis of steroid hormones adrenal glands (see Adrenal glands) led to opening of unknown before stages of a steroidogenesis and their sequence and allowed to create the new scheme of biosynthesis of steroids (see). He carried out studying of influence of adrenocorticotropic hormone on biosynthesis of corticosteroids normal and at endocrine diseases. N. A. Yudayev was an initiator of studying in the USSR of chemistry and biochemistry of hormones of hypo-talamo-pituitary system. Under its management and with direct participation primary structure of a number of proteinaceous and peptide hormones is deciphered and for the first time in the USSR chemical synthesis of insulin of the person is carried out. Under the leadership of N. A. Yudayev original methods of synthesis of the main natural prostaglandins and their analogs are developed, it studied important mechanisms of effect of prostaglandins, including on specific receptors of hormones.

N. A. Yudayev was vice-president Vsesoyuznogo scientific about-va endocrinologists, the member of council Vsesoyuznogo biochemical about-va, the honorary member of a row foreign and international scientific about-in, and also the member of editorial board and the editor-in-chief «Endocrinology» of BME, the editor-in-chief of the Problems of Endocrinology magazine redotdet.

«the sign of Honour» and medals is awarded by awards of the October Revolution, the Labour Red Banner.

Works: Biosynthesis, emergence in onto-and phylogenesis, distribution and value for function of muscles of a kariozin and anserine, a yew., M., 1950; Biochemistry of steroid hormones of bark of adrenal glands, M., 1956; Chemical methods of definition of steroid hormones in biological liquids * M., 1961; Modern questions of endocrinology, century 3 — 5, M., 1969 — 1975 (bus

of a number of hl. sovm. with other and an edition); Biochemistry of hormonal regulation of a metabolism, Vestn. Academy of Sciences of the USSR, No. I, page 29, 1974; Biochemistry of hormones and hormonal regulation, M., 1976 (edition); Biochemical bases of a pathogeny of a diabetes mellitus, Rubbed. arkh., t. 49, No. 5, page 6, 1977; Hormones, their mechanism of action and regulation of a metabolism, Vestn. USSR Academy of Medical Sciences, No. 7, page 3, 1980; Adenilattsiklazny system as a universal link in the mechanism of effect of hormones, in the same place, No. 2, page 3, 1983 (sovm., with Afinogenova S.A.).

The bibliography: Nikolay Alekseevich Yudayev (To the 60 anniversary since birth), Vopr. medical, chemistry, t. 20, jfi 1, page 102, 1974.

O. N. Yudenich.