At RAIDS — derivative urea, in a molecule a cut hydrogen atoms are replaced with acid radicals, with the general formula Rx • HN • WITH • NH • B2 where Rt and R2 — acid radicals. At. nek-ry dicarbonic to - t (see. Carboxylic acids), barbituric to - that, the mesoxalyl urea and other connections relating to At., possess expressed pharmakol. properties. In medicine many At. and nek-ry they galogenozameshchenny are applied as the pharmaceuticals possessing somnolent and sedative action.
Varbiturovy to - that (a synonym: the ureide
low-new to - you, malonyl urea) is formed of urea (see) and ma-lonovy to - you. At substitution of hydrogen in a molecule barbituric to - you at the fifth carbon atom hydrocarbon radicals of a fatty or aromatic series form the barbiturates (see) possessing sedative, somnolent, to a protivos road and narcotic action.
Mesoxalyl urea (see) — the ureide mesoxalic to - you (mesoxalyl urea) is a product of a catabolism uric to - you. Mesoxalyl urea is widely used in medical - biol. researches for modeling of a diabetes mellitus on animals, so-called alloxanic diabetes (see Diabetes).
From heterocyclic At. the greatest interest is of uric acid (see), caffeine (see), theobromine (see), theophylline (see). In a human body uric to - that is an end product of purine exchange (see). Caffeine (see), theobromine (see), theophylline (see) in medicine is applied as pharmaceuticals.
Bibliography: Karrer P. A course body
of chesky chemistry, the lane with it., L., 1962; Stepanenko B. N. Course of organic chemistry, p.1, page 382, M., 1976.
L. I. Miloslavskaya.