URATE HEART ATTACK (Latin infarctus, from infarcire to fill, fill) — accumulation in renal nipples of crystals of uric acid. M and. newborns can arise in the first days of life owing to disintegration of nuclear erythrocytes and the expressed intensity of purine exchange (see. Urate diathesis ). At the same time signs of a nefrogidroz, an intersticial inflammation and a renal failure, as a rule, are not observed. At adult M. and. develops seldom, sometimes meets at inf. diseases, to gout (see), leukoses (see), especially at treatment by antineoplastic means, and also at genetically caused deficit gipoksantin-guanin-phosphoribosyl-transferase and as a result of disintegration of purine bases at disturbances of protein metabolism.
Macroscopically in renal pyramids at M. and. the golden-yellow radial strips meeting to tops of renal nipples are found. At microscopic examination they have an appearance of accumulations of birefringent crystals of spherical shape to dia. 10 — 20 microns, are frequent with impurity of protein and desquamated a nefroteliya, filling renal tubules.
Bibliography: Diseases of kidneys, under the editorship of G. Mazhdrakov and N. Popov, lane with bolg., page 644, Sofia, 1976; And in and N about in with to and I am T. E. and A. V Tsinzerling. Pathological anatomy (disease of children's age), page 21, M., 1976; M and t in e e in M. P. and To about r the island and N and N. A. An urate heart attack of a kidney, in book: Bases nefrol., under the editorship of E. M. Tareeva, t. 2, page 780, M., 1972; E m m e r-s o n B. T. a. R o w P. G. An evaluation of the pathogenesis of the gouty kidney, Kidney Internist, v. 8, p. 65, 1975, bibliogr.; M a n z k e H. o. Uric acid infarctions in the kidneys of newborn infants, Europ. J. Pediat., v. 126, p. 29, 1977.
L. H. Zymin.