UNDECYLENIC ACID (Acidum undecylenicum; synonym:
Myko-septin, Undecyl) — antifungal means. undets-Yu-enoyevaya to - that; Stsn2o02:
The colorless or yellowish-brown oily liquid with a characteristic smell hardening during the cooling (t ° hardenings 22 °); pier. weight (weight) 184,28. The rastvorima in 95% alcohol and ether is almost water-insoluble very easily.
Has a fungistasis. At a combination At. to. with its zinc or copper salts fungistatic activity At. to. raises.
The drugs containing At. to., apply to topical treatment of fungus diseases of skin. Will more difficultly respond to treatment drugs U. to. fungal infections of hair. Indications to use of drugs U. to. various dermatomycoses, napr, bottom, inguinal and intertriginozny forms of an epidermophitia, a trichophytosis and a microsporia of skin are.
The ointments containing At. to., rub in affected areas of skin 2 times a day in the morning and in the evening within 15 — 20 days (depending on terms of disappearance of pathogenic fungi at a mycologic research). If necessary the course of treatment is repeated by 2 — 3 times with intervals in 2 — 3 weeks. During treatment, and also after its termination it is recommended to powder the struck places powder Dustundanum.
At. to. and its drugs usually do not cause side effects and at rational use do not render local irritant action. It is necessary to be careful, however, at treatment pain
ny with extensive damages of skin, especially at acute a disgidro-ta ches which to a form or an ekzematiziro-bathing epidermophitia, in order to avoid an aggravation of process.
In medical practice apply the following dosage forms containing At. to.
Zincimdanum — the ointment of grayish-white color containing 10% undecylenic to - you, 10% of zinc salt U. to., 10% of anilide salicylic to - you and an ointment basis to 100%.
Form of release: in glass jars with densely screwing up covers.
Undecinum — the ointment of greenish-blue color containing 8% undecylenic to - you, 8% of copper salt U. to., 4% p-hlorfeni-lovogo ether of glycerin and an ointment basis to 100%.
Form of release: in glass jars with polyethylene covers.
Mycoseptinum — the ointment containing apprx. 5% undecylenic to - you, 20% of zinc salt U. to. and an ointment basis to 100%.
Form of release: in tubas on 30 g.
Dustimdanum — the powder containing 5% undecylenic to - you, 10% of zinc salt U. to., 10% of anilide salicylic
to - you and 75% of talc.
See also Antifungal means. Ya. M. Polukhina.