From Big Medical Encyclopedia

TAURINE — mercaptoethanol, or taurine, is synthesized in a human body and animals, plays an essential role in the course of digestion and digestion of fats and lipids.

T. it is formed as a result of oxidation of sulphhydryl group cysteine (see) and the subsequent decarboxylation cysteic to - you (see. Decarboxylation ):

Physiological role of T. in a human body consists in formation of parpy connections (conjugates) with bile acids (see). Synthesized taurocholic to - that has ability to be dissolved in water that does possible absorption bilious to - t in blood in an ileal gut. It promotes enterogepatnchesky, or portal and biliary circulation bilious to - t, as a result cover 85 — 90% of all bilious to - t bile (see) it reabsorbirutsya in intestines and repeatedly cosecretes as a part of bile.

Abundance of taurinovy conjugates in bile increases at a high-protein diet; at the diseases which are followed by proteinaceous insufficiency, the maintenance of taurinovy conjugates in bile decreases. Corticosteroid hormones cause increase in fraction of taurinovy conjugates in bile in comparison with glycine conjugates (see. Glitsin ). The ratio of taurinovy and glycine conjugates in bile depends also on the content in blood of hormones of a thyroid gland.

Normal at the person with urine on average 156 mg of T are removed per day.

See also Lipometabolism , Liver .

Bibliography: Berezov T. T. and Korovkin B. F. Biological chemistry, page 480, M., 1982; To r yu Zh. Biokhimiya, the lane with fr., page 432, M., 1979; H e N and c e with-to at K. D. Organic chemistry, the lane from Romanians., t. 2, page 401, M., 1963.

N. G. Budkovskaya.