ShAPOT Vladimir Sergeyevich

From Big Medical Encyclopedia

ShAPOT Vladimir Sergeyevich (sort. in 1909) — the Soviet biochemist, the oncologist, the member correspondent of AMH (1965). The member of the CPSU since 1941.

In 1934 ended biological f-t Leningrad un-that. In

1934 — 1937 the employee Fiziologicheskogo in-that Leningrad un-that worked in Ying-those experimental medicine under the leadership of V. A. Eigeljgard-t In 1937 — 1941. In days of the Great Patriotic War the chief of chemical service of a regiment, the doctor-laboratory assistant evakogospitalya. From 1946 to 1953 directed VIEM laboratory, and in 1953 — 1960 managed department of biochemistry Vitebsk medical in-that. Dr.Sci.Biol. (1948); professor (1954). Since 1960 manages laboratory of biochemistry of tumors of All-Union oncological scientific center of the USSR Academy of Medical Sciences.

B.C. Shapot — the author of the St. 240 scientific works devoted to biochemical problems of experimental and theoretical oncology, and also chemistry nucleinic to - t and nucleoproteids. The specific ribonuclease catalyzing splitting of RNA of small subunit of ribosomes is discovered by them, the model of the molecular mechanism of participation of cytoplasm in regulyation of activity of genes is offered, by means of an original method of allocation nucleinic to - existence of alternative states in nuclear structures of the based and sharing cells is established to t from their complex with proteins. Wide recognition was gained by its researches of relationship of a tumor and an organism at various system levels, napr, mechanisms of «capture» by a tumor of glucose.

V. S. Shapot is board member Vsesoyuznogo scientific medical about-va oncologists, the chairman of the All-Union problem commission on biochemistry of tumors and biology of a tumor cell of Scientific council on malignant new growths at Presidium of the USSR Academy of Medical Sciences, member correspondent. The American association on a research of cancer, the editor redotdet «Oncology» of BME, and also the member of editorial councils of a number of domestic magazines.

It is awarded by awards of the Labour Red Banner, the Red Star and medals.

Works: About the nature of special sensitivity of a brain to oxygen insufficiency, Usp. sovr. biol., t. 34, century 2(5), page 244, 1952; Nucleases, M., 1968; Biochemical aspects of tumoral growth, M., 1975; Nucleocytoplasmic relations and transport of RNA, Usp. sovr. biol., t. 94, century 1(4), page 3, 1982 (sovm. with Liechtenstein A. V.); About interrelation and releasers of frustration of a homeostasis and a tumoral organism, Arkh. patol., t. 45, No. 8. page 3, 1983.

Bibliography: Vladimir Sergeyevich Shapo'g (To the 70 anniversary since birth), Vopr. onkol., t. 25, No. 8, pages 1 18, 1979.

B. A. Klyashchitsky.