From Big Medical Encyclopedia

SYRINGADENOMA (Greek syrinx, syringos pipe, tube + adenoma; synonym: papillary syringadenoma, syringocystadenoma, papillomatous siringotsistadenomatozny nevus, papillary cystadenoma, syringocystoma, papillary adenoma of a sweat gland, warty fistulovegetiruyushchy gidradenoma) — benign tumor of skin, coming from channels of sweat glands.

The page meets seldom, usually at young and children's age though it can be observed at persons of advanced and senile age. It is localized preferential on a pilar part of the head and it is frequent in a zone of an arrangement of apocrine sweat glands (axillary poles, area of mammary glands, inguinal areas), is much more rare on other body parts. S.'s combination to malformations and other epithelial tumors is possible skin (see) — bazaliomy (see), seborrheal papilloma, ekkrinny poromy, etc.

There is no uniform view of S.'s histogenesis. Most of researchers considers that S. develop on the basis of a malformation sweat glands (see) or their primary epithelial rudiment, nek-ry, on the contrary, believe that S. can develop also from completely created apocrine and ekkrinny sweat glands.

Macroscopically S. represents single education like a small knot or a plaque to dia. 0,5 — 2 cm of grayish or grayish-yellow color, a dense consistence which are quite often towering over skin with a pulled melkobugristy or granular surface, sometimes ulcerated.

Fig. 6. Microdrug of a papillary sirpngoadenoma: papillary growths with limfoplazmotsptarny infiltration and a plethora of vessels (yellow color) of a stroma; shooters specified zhelezistopodobny tubular structures; coloring hematoxylin-eosine; x 100.

Microscopically distinguish papillary and tubular S. Papillyarnaya S. it is formed by the cysts and zhelezistopodobny tubular structures which are located under epidermis (tsvetn. fig. 6). Cysts and tubes are covered by a two-row epithelium: the inner layer is made by cubic or cylindrical cells, a periblast — the flattened cells. Idiosyncrasy of S. of this type is existence in cysts of nipples. At an ulceration of a tumor nipples can act over the surface of skin. Sometimes cysts and nipples are covered by a multilayer flat epithelium. In S.'s cells find a glycogen and slime. The mucous contents rich with a glycogen are defined also in cavities of cysts. Idiosyncrasy of papillary S. is massive limfoplazmo-cytic infiltration of a stroma of papillary outgrowths. Tubular S. consists of the tubes intertwining and anastomosing with each other covered by a two-row epithelium. Nek-ry tubes kistozio are expanded, but in them there are no papillary outgrowths. Their contents are rich with a glycogen and mucin. The metaplasia of an epithelium in multilayer flat is sometimes noted.

Wedge, current long, usually long-term. Sometimes patients complain of a local itch or easy morbidity. Accession of the inflammatory phenomena of a tsra an ulceration of skin in a zone of a tumor can be followed by acceleration of its growth.

Treatment operational.

Forecast favorable. During incomplete removal of S. can recur. Authentic data on S.'s malignancy are absent.

Bibliography: Apatenko A. K. Epithelial tumors and malformations of skin, page 111, M., 1973; About l about in and D. I N. Epithelial tumors of skin, Chisinau, 1958; Gubareva of A. V. Slringade-noma of skin, Arkh. patol., t. 28, No. 12, page 48, 1966, bibliogr.; Sh t and to e l - e r A. A. K to a question of adenomas of sweat glands (gidradenoma), the Russian doctor, t. 8, No. 44, page 1494, 1909, bibliogr.; L e-V e r W. F. a. Schaumburg-Le-V e of G. Histopathology of the skin, p. 510, Philadelphia, 1975.

V. M. Blinov.