STERN Lina Solomonovna (1878 — 1968) is the Soviet physiologist, the academician of Academy of Sciences of the USSR (1939) and USSR Academy of Medical Sciences (1944), zasl. scientist of RSFSR (1934), winner of the State award USSR (1943). The member of the CPSU since 1938.
In 1903 ended Geneva un-t and worked in the same place at department of physiological chemistry as the assistant (since 1904), the associate professor (since 1906), professor (from
1917 to 1925).
In 1925 L. S. Stern moved to the USSR. From 1925 to 1948 managed department of normal physiology of the 2nd MMI. At the same time in 1926 — 1928 in-that directed department of biochemistry Moscow infectious diseases of I. I. Mechnikov (nowadays Moscow scientific research institute of vaccines and serums of I. I. Mechnikov) and department of biochemistry Moscow medicobiological in-that (1926 — 1930), in 1929 — 1948 there was the organizer and the first director Ying-that Narkompros's physiology of RSFSR. In 1929 — 1938 L. S. Stern participated in the organization and in-those were the head of department of age physiology in the Central scientific research institute of motherhood and an infancy (nowadays Ying t of pediatrics of the USSR Academy of Medical Sciences) and department of general physiology in All-Union experimental medicine. From 1954 to 1968 L. S. Stern headed department of physiology Ying-that biophysics of Academy of Sciences of the USSR.
L. S. Stern is an author apprx. 500 scientific works, including several monographs. She is one of founders of the doctrine about gisto-gematichesky barriers (see. Barrier functions). In 1921 L. S. Stern and R. Gauthier entered the concept «blood-brain barrier» designating fiziol. the mechanism which is selectively regulating a metabolism between blood and structures of the central nervous system and carrying out protective to funk-day, interfering with penetration into cerebrospinal liquid and into neurons of a head and spinal cord of the substances, alien for an organism, getting to blood and the toxic metabolites which are formed in an organism at nek-ry patol. states (see the Blood-brain barrier). Using various methods, including a radioisotope-ny and the method of a direct injection improved by it in cerebral cavities of various hormones, mediators, vitamins, salts and other substances, L. S. Stern established features of functioning of a blood-brain barrier and defined its role in formation of a functional condition of various nerve centers. In scientific activity L. S. Stern studying of dynamic constancy of internal environment of an organism (see the Homeostasis), development of the theory of tissue respiration, studying of neurohumoral mechanisms of regulation of functions of a dream and wakefulness, questions of aging and longevity, and also a pathogeny and therapy of shock, impact on an organism of ionizing radiation figured prominently.
The state award USSR it is conferred for the works devoted to studying of a blood-brain barrier.
L. S. Stern was a member of many Soviet and foreign scientific about-in, honourable doctor Zhenevsky un-that (1960), the editor of a redotdel «Biological physics. Physiology» 1 prod. BME was also redotdet by «Physiology» of the 2nd prod. BME, editor-in-chief (1935 — 1949) of the «Bulletin of Experimental Biology and Medicine» magazine.
It is awarded by awards of the Labour Red Banner, the Red Star and medals.
Works: A blood-brain barrier, M. — ■ D., 1935 (sovm. with other); The Direct medium of bodies and fabrics, the Physiological mechanisms defining its structure and properties, Izbr. works, M., 1960.
Bibliography: Lina Solomonovna Stern, sost. N. V. Smirnova, M., 1960; Century since the birth of the academician L. S. Stern, Fiziol. zhurn. USSR, t. 55, No. 9, page 1391, 1979. L. M. Chuppina.