SCLEREDEMA of adults
SCLEREDEMA of adults (scleroedema adultorum; Greek skleros firm, dense + oidema a tumor) — seldom found dermatosis connected with infectious and toxic trophic defeat of collagenic fabric which is shown hypostasis and consolidation of a derma and hypodermic cellulose. A. Bushke in 1902 is for the first time described.
Etiology and pathogeny are not found out. Usually the dermatosis develops after the postponed acute infections (quinsy, flu, etc.); can appear after a pyoderma. Significance of pathology of hemadens is attached.
At gistol. a research in a derma and hypodermic cellulose puffiness, homogenization and fragmentation of collagenic fibers are found (see. Collagen ). The painted substance slizistopodobny metokhromatichno, a ratio hyaluronic to - you comes to light and hyaluronidases it is broken; there is a weak perivascular infiltration without obliteration of vessels. In epidermis in places, especially in follicles, can be weak hyperkeratosis (see).
The disease begins with emergence of edematous thickenings of a pasty consistence of skin with a clear boundary (further possibly involvement in process of fastion and muscles). Color of affected areas of skin nacreous-white or vos-kovidno-yellow. Skin does not gather in folds, becomes firm, its drawing is maleficiated. More often process begins with head skin and a neck, gradually extending to a face (mask-like face), a breast, a back; mucous membranes of eyes, oral cavities, and also language can be involved in it (makroglosspya). The general phenomena of intoxication and morbidity are absent. The disease progresses during 2 — 4 weeks, lasts till 1 year and more.
Diagnosis establish on the basis a wedge, the picture confirmed in doubtful cases gistol. research of skin. Pages differentiate with myxedema of skin (see), dermatomyositis (see), scleroderma (see), etc.
The disease has tendency to spontaneous treatment; the atrophic phenomena of skin after the postponed dermatosis are not noted.
Bibliography: Kalamkaryan A. A. and Chistyakova I. A. About a scleredema of adults Bushke, Vestn. dermas, and veins., No. 9, page 6, 1977, bibliogr.; M and sh to and l-l e y with about L. N N. Private dermatology, page 437, M., 1965; Priests of L. Synthetic dermatology, the lane with bolg., Sofia, 1961; Skripkin Yu. K. Skin and venereal diseases, M., 1979; Buschke A. Uber Scleroedem, Berl. klin. Wschr., S. 955, 1902; P e 1 1 e r a-noS., PezzuoloM. e Moret-t i G. Un caso di scleredema Buschke, G. ital. Derm., v. 114, p. 105, 1979, bibliogr.
Yu. K. Skripkin.
SCLEREDEMA of newborns
SCLEREDEMA of newborns (scleroedema neonatorum; Greek skleros firm, dense + - oidema a tumor) — the condition of the newborn which is characterized by limited consolidation of skin and hypodermic cellulose, and also emergence of hypostases; it is observed at premature children.
Etiology and pathogeny finally are not found out. S.'s development is promoted by overcooling of an organism and a hypoproteinemia.
Page. it is shown emergence in the first days of life of the child of consolidations of skin and hypodermic cellulose on the outer side of hips, sometimes buttocks, to-rye unlike scleremas (see) do not tend to generalization. Skin is strained, cold to the touch, during the pressing by a finger on it there are poles disappearing very slowly.
At good leaving, warming and healthy nutrition of S. disappears in several weeks.
Prevention The page consists in the prevention of cooling.
See also Swelled .
Bibliography: The multivolume guide to pediatrics, under the editorship of Yu. F. Dombrovskaya, t. 2, page 478, M., 1961; P about p x r and - with t about in the Item. Skin diseases at children's age, the lane with bolg., page 221, Sofia, 1963; Shteynlukht L. A. and Zverkov F. A. Diseases of skin of children of chest age, page 38, L., 1979.
V. P. Bisyarina.