SALICYLIC ACID

From Big Medical Encyclopedia

SALICYLIC ACID (Acidum salicylicum; GF X) — antiseptic, keratoplastichesky and keratolytic agent. au-Oksibenzoynaya to - that; With 7 H 6 O 3  :

White small acicular crystals or inodorous light crystal powder. We will dissolve in water a little, we will dissolve in a boiling water, it is easily alcohol-soluble, ether, we will difficult dissolve in chloroform; t pl 158 — 161 °; pier. weight (weight) 138,12.

At external use of S. to. renders the irritating effect, suppresses secretion of sweat glands and shows moderate antimicrobic activity. In low concentrations (1 — 2%) has keratoplastichesky, and in high concentration (10 — 20%) keratolytic properties. At resorptive action of S. to. causes analgesic, febrifugal and antiinflammatory effects, however in medical practice for these purposes it is not used since at different ways of introduction has strong local irritative effect. As analgesic, febrifugal and anti-inflammatory drugs use nek-ry derivative S. to., napr, acetylsalicylic acid (see), sodium salicylate (see), Salicylamidum (see), to-rye in this respect surpass in S.'s activity to. also have considerably less expressed local irritative properties.

Page to. apply only outwardly as the antiseptic, irritating, keratoplastichesky and keratolytic means in powders (2 — 5%), ointments and pastes (1 — 10%), and also in the form of spirit solutions (1 — 2%).

Form of release: powder. Keep in well corked container protecting from effect of light.

Page to. is also a part of a number of the officinal preparations which are released domestic chemical - pharm. industry. Are among such drugs: Galmaninum, corn liquid, kamfotsin, a corn adhesive plaster Salipod, paste salicylic and zinc, paste salicylic sulfur-zinc, paste salicylic and zinc with naftalanny ointment.

Galmaninum (Galmaninum) — the powder containing salicylic to - you are the 2nd h, zinc oxides 10 of h, talc and starch on 40 h. It is applied outwardly at perspiration of legs.

Form of release: in boxes on 50 g.

Kamfotsin (Camphocinum) — linimentum containing salicylic to - you are the 3rd, oils of castor 5 g, turpentine and methyl salicylate on 10 g, camphor of 15 g, tincture of pepper siliculose to 100 g. Apply outwardly as irritating and a revulsive.

Form of release: in bottles of orange glass on 80 ml.

Corn liquid — the liquid plaster containing S. to. and alcohol of ethyl 95% on 10 g, tetraethyl-diamino-triphenyl-carbohydride sulfate of 0,1 g, a collodion to 100 g. Apply to a helotomy.

Form of release: in bottles on 5 — 10 ml. Keep in the cool place far from fire.

Corn adhesive plaster Salipod (Emplastrum adhaesivum ad clavus «Salipodum») — the smeared plaster containing salicylic to - you are 32,8 g, are gray besieged 8,1 g, rubber of natural 22,4 g and nek-ry aids to 100 g. Apply to a helotomy.

Form of release: in packages from paper.

Paste salicylic and zinc (Pasta Zinci salicylata; a synonym Lassar's paste) — the paste containing salicylic to - you are the 2nd h, zinc oxide and starch on 25 h, vaseline of 48 h. Apply outwardly as antiseptic and local anti-inflammatory drug.

Paste salicylic sulfur-zinc — the paste containing salicylic to - you are 0,6 g, pastes of zinc 20 g are gray cleared 5 g. Apply outwardly at diseases of skin.

Paste salicylic and zinc with naftalanny ointment — mix of 1:1 pastes salicylic and zinc and ointments naftalanny. Apply outwardly as antiseptic and local anti-inflammatory drug.

See also Keratolytic, keratoplastichesky means .


L. D. Shipilova.

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