From Big Medical Encyclopedia

RECIPE (receptum; lat. recipere to receive) — written, the established form (on the printing form) the address of the doctor (the paramedic, the midwife, the dentist) in a drugstore about issue of medicine in a certain dosage or production of a dosage form with the indication of a direction of use of medicine; is the basis for issue from drugstores of the majority of pharmaceuticals.

Also released rules of invoicing of recipes for ambulatories to them drugs are established by the order M3 USSR No. 175 of February 25, 1982. «About measures for further improvement of provision of medicines of the population and treatment and prevention facilities». The appendix 2 to this order established two forms of prescription forms: for issue of pharmaceuticals for total cost to adults and children; for issue of pharmaceuticals free of charge or on favorable terms.

Rubles write in Latin, and a route of administration of medicine — in the Russian or Russian and national languages with the indication of a dose, frequency, time of reception (to or after food) and duration of a course of treatment. It is necessary to write R. with readable, fair writing, ink or a ball pen on the uniform form of 105x148 mm in size with obligatory filling of all columns provided in the form. On the left side of the prescription form the field for a rating of the pharmaceuticals provided from a drugstore is left.

Rubles on pharmaceuticals, to-rykh are a part the narcotic and equated to them substances, irrespective of a type of a dosage form, write out on the special forms (which are on the strict account), No. 1230 established by the order M3 USSR of December 27, 1976 of a sample with the appendix of a stamp, round stamp of medical institution and the personal press of the doctor. The ruble shall be written by a hand of the doctor signing it. Besides, on such R. there has to be a signature of the chief physician or manager of department to lay down. - the prof. of establishment.

River on the medicines containing toxic agents of the list A (see. And ), write out on the prescription forms having a stamp and press to lay down. - the prof. of For Recipes institution, and also the signature and the personal press of the doctor. If medicine contains alcohol, R. write out on prescription forms with the press of For Recipes medical institution, the signature and the personal press of the doctor. River on strong substances of the list B (see. B ), including antibiotics and streptocides, shall have a stamp of medical institution, the signature and the personal press of the doctor. Corrections in R. cannot be allowed.

Rubles for issue of drugs free of charge or on favorable terms write out in duplicate (under a carbon paper). The ruble and the copy are assured by the sign and seal of the doctor, and also the press of For Recipes medical institution. At the same time the doctor is obliged to bring the contents and number P in a case history (the out-patient card).

In R. enter a surname, a name, a middle name and age of the patient, date (year, month, number), a surname, a name and a middle name of the doctor. These designations are put at the beginning of R. and carry the name of a text, the title (inscriptio). Then the address to the druggist — recipe follows that means «take», in abbreviated form designated by the letters Rp. Then list the Latin names of substances entering this R. (in a genitive case) with the indication of their quantity. For injection solutions the designation «pro injectionibus» accepted in GFH in R. is not specified since the subsequent instruction about a form of release (in ampullis) and the corresponding instruction in a signature on a route of administration is meant that the injection solutions which are released according to R. shall meet requirements of GF imposed to such dosage forms.

If the dosage form includes several ingredients, at first prescribe the main active ingredient (basis). After it list aids (adjuvans), and also the substances improving taste, a smell of a dosage form. The last are called correcting (corrigens). A dosage form (see. Dosage forms ) is defined in most cases by medicine. However in some cases there can be a need for use of constituens, i.e. the substance giving to this medicine a certain consistence. Such substance in the list of ingredients of a dosage form is specified on the last place. Further, depending on a form, edge it has to be given to the registered pharmaceuticals, specify the accepted designations of those manipulations, to-rye it is necessary to make. E.g., Misce ut fiat unguentum (in abbreviated form: M. f. ung.), what designates «Mix that ointment turned out». Such designations call subscriptio — the instruction to the druggist about a way of preparation of a dosage form.

A dose of medicinal substance (see. Doses ) designate in the decimal count system. One is accepted to a mass unit (weight) grakhmm that in R. is designated by 1,0. During the dosing of drugs use also smaller sizes: 0,1 — one decigram; 0,01 — one centigram; 0,001 — one milligram; 0,0001 — one detsimilligramm; 0,00001 — one santimilligramm; 0,000001 — one microgram. Amounts of liquid substances specify in milliliters (ml), grams or drops. Quantity of drops designate in the Roman figure, before a cut write gtts (reduction of the word guttas — «thaw» in an accusative case of plural), e.g., of gtts V (five drops).

During the invoicing of the pharmaceuticals dosed in terms of action (PIECE) instead of weight or volume quantities specify the number of PIECE in R.

Sometimes the doctor does not specify quantity of constituens (e.g., in suppositories, pills), providing to the druggist to take it how many it is necessary; in this case write q. s. (quantum satis), t. e. how many it will be required. This designation can be used only concerning indifferent substances.

If several medicinal substances write out in the same dose, then designate its digital size only once after the name of the last substance. For designation that noted quantity belongs also to all other listed substances put a sign aa (reduction of armor. the words ana — equally).

Doses of the medicinal substances entering a copy-book specify on the right side of the prescription form near the name of medicinal substance (or is one line lower).

When the maximum dose of toxic or strong agents is exceeded, it is necessary to specify their quantity by a copy-book with addition of an exclamation mark and the signature of the doctor that this dose is written out not accidentally. If the written-out dose is not validated, the druggist reduces a dose of substance (to 50% of the highest single dose specified in GF).

At the end of R. do the instruction to sick or medical staff about a direction of use of medicine. In this part P., the called signature (signatura), shortly and more exhaustively specify: 1) a dosage (e.g., on 1 powder, on 1 tablet, on 1 table, l., on 20 drops etc.); 2) time and frequency of reception of medicine (how many once a day, to food or after food, for the night etc.); 3) a route of administration of drug (intravenously, subcutaneously, to enter slowly etc.).

On one prescription form for issue of drugs for total cost it is allowed to prescribe only one medicine containing toxic or narcotic agent, or two medicines containing simple or strong substances.

On one prescription form for issue of drugs it is is free or on favorable terms allowed to prescribe only one medicine.

If the condition of the patient demands immediate issue of medicine from a drugstore, then on the prescription form at the left above write cito! (soon!) or statim! (immediately!). In this case pharmaceuticals shall be made and released out of turn.

When the doctor prescribes medicine for himself, on the prescription form in the column «Full Name Patient» write Pro autore (For the author).

The medicines given in GF and produced chemical - pharm. the industry in finished form, call officina ofitsinalny (Latin a drugstore). The dosage forms produced on the copy-books made at the discretion of the doctor are called by magister main (Latin by the teacher, the mentor). According to it distinguish ofitsinalny and main copy-books of drugs.

There are (full) and reduced (short) copy-books developed. Specify a dosage form, the name of medicinal substance, concentration and total quantity in the reduced copy-book. In the developed copy-book list the ingredients entering medicine, their quantity, then do the instruction to the druggist about preparation of a dosage form.

In R. only such reductions are admissible, to-rye cannot cause any misunderstanding at production of medicine. The list of the main prescription reductions is provided in the order M3 USSR No. 175 of February 25, 1982 (appendix 1).

R. coming to a drugstore is checked concerning a dosage of poisonous, strong and other means, by compatibility of the prescribed substances. Besides, R. tax and nomerut the future issue of receipt in a drugstore.

Incorrectly written out R. in a drugstore is cancelled and put on it a stamp «The recipe is invalid». Such R. register and report about them in to lay down. - the prof. establishment where they were written out.

Pharmaceuticals for the patients who are on hospitalization release free of charge from drugstores of medical institutions according to requirements (recipes) signed by the chief physician or the manager of department.

Bibliography: Mashkovsky M. D. Pharmaceuticals, p.1 — 2, M., 1977; Harkevich D. A., M and y with to and y V.V. and Muratov V. R. General compounding, M., 1982.

D. A. Harkevich