QUATERNARY AMMONIUM COMPOUNDS

From Big Medical Encyclopedia

QUATERNARY AMMONIUM COMPOUNDS — organic derivatives of salts of ammonium, in to-rykh all hydrogen atoms are replaced by organic radicals.

In medicine (see) apply surface-active quaternary ammonium compounds to disinfection. In our country make katamin A B (alkyldimethylbenzylammonium chloride), degmin (alkilde-tsilkarboksimetilenammony chloride), cetylpyridinia chloride, it is scarlet - kamon DS-u (alkoksimetildietilme-tilammony methosulphate). Production of various compositions — Degmicidum (on the basis of a degmin) and a nirtana is arranged (on the basis of alkiltrimetilammoniya of chlorides).

H ampere-second. — white powders or inodorous pastes, well water soluble, resistant at storage, possess bacteriostatic, bactericidal and detergency.

For disinfection at intestinal and droplet infections of a bacterial etiology use

0,5 — 3% of Ch. of ampere-second., they are applied also to disinfecting of the equipment and ware on milk, canning and breweries, by production of vitamins, antibiotics and food acids. H ampere-second. not letuch, but at hit on skin and a mucous membrane in the form of an aerosol cause irritation therefore work with them needs to be carried out in a dressing gown, a kerchief, gloves, goggles, a respirator (universal RU-60 of M or RPG-67), it is possible to enter the room in 30 — 40 min. after processing.

See also Desinfectants.

Bibliography: In and sh to about in V. I. Antimik

robny cure and methods of disinfection for infectious diseases, page 37, M.,

1977; Green S. A., P and in l about in A. A. and Gushchin N. V. Cationic surfactants, M., 1979;

Skvortsova E. K., etc. Antimicrobic properties of drug nirtan, in book: Probl. disinfection and sterilizations, under the editorship of V. I. Vashkov, t. 1, century 21, page 80, M., 1971. N. F. Sokolova.

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