From Big Medical Encyclopedia

POLYGLANDULAR INSUFFICIENCY (Greek poly is a lot of + armor. glandula of iron; synonym: multiglandular insufficiency, polyglandular syndrome) — the clinical syndrome caused by decrease or total absence of formation of tropny hormones a hypophysis as a result of infectious, toxic, vascular, traumatic and other defeats of gipotalamo-pituitary area. The syndrome is characterized hypothyroidism (see), a hypocorticoidism (see. Adrenal glands ) and hypogonadism (see), decrease in secretion of a growth hormone and prolactin, very often P. the N is followed by a cachexia.

See also Apituitarism , Hypothalamic syndrome , Pituitary cachexia , Shikhena syndrome .

Bibliography: Vasyukova E. A. Cerebral and pituitary diseases, M., 1952; Grollman A. Clinical endocrinology and its physiological bases, the lane with English, M., 1969; The Guide to clinical endocrinology, under the editorship of V. G. Baranov, L., 1977.