From Big Medical Encyclopedia

POLYDIPSIA (grech, poly is a lot of + dipsa thirst; synonym potological thirst) — the pathological increased thirst and the related consumption of excessively large amount of water (sometimes St. 20 l a day).

The item arises owing to irritation of the drinking center in connection with disturbance in an organism water salt metabolism (see), a cut leads to increase osmotic pressure (see) blood and to irritation osmoreceptors (see).

Origins of P. at different patol. states it is various. At hyper aldosteronism (cm.) The item arises owing to increase in blood of concentration of sodium chloride; at a diabetes mellitus (see. diabetes mellitus ) — as a result of a hyperglycemia, leads edges to severe dehydration of fabrics and polyurias (see) owing to increase in osmotic pressure of urine. The polyuria and a polydipsia (a so-called poliurodipsiya) are non-constant symptoms. The polyuria as P.'s reason at not diabetes mellitus is connected with decrease in secretion of antidiuretic hormone (ADG) or vasopressin (see).

Distinguish P. acute (short-term) and chronic (long). Acute P. is observed at considerable disturbances of a water-salt homeostasis, napr, owing to a plentiful pototdeleniye, pernicious vomiting, a profuse diarrhea, big blood losses; chronic P. — at long disturbances of a vodnosolevy homeostasis, napr, at not diabetes mellitus (see. Diabetes not sugar ), hypothalamic syndrome (see), adiposogenital dystrophy (see), at damage of kidneys.

P.'s treatment is directed to the basic disease which caused disturbance of a water-salt homeostasis.

See also Thirst .

Bibliography: Biochemistry of hormones and hormonal regulation, under the editorship of N. A. Yudayev, M., 1976; D and in and d e of N to about in and - To at l ý-to about in and E. F. Diencephalic epilepsy, JT., 1959, bibliogr.; Tsav-l about in I. P. Complete works, t. 3, book 1, page 147, M. — L., 1951; Physiology of endocrine system, under the editorship of V. G. Baranov, L., 1979; Labhart A. Klinik der inneren Sekretion, B. u. a., 1978; Textbook of endocrinology, ed. by R. H. Williams, Philadelphia, 1974.

3. I. Yanushkevichus.