PHOTODERMATOSES (Greek phos, photos light - f-derma, dermatos skin + - osis; synonym: light diseases, aktinodermatoza) — the diseases of skin caused by her hypersensitivity to sunlight.
Hypersensitivity of skin is caused by fotosensibilizato-ra (see Fotosensibilization), to the Crimea many dyes (e.g., eosine, methylene blue), nek-ry salts of manganese, iron, uranium, mercury, arsenic, coal tar and its products (e.g., naphthalene and green oils), piotsianida (waste products of a pyocyanic stick) photosensitizing means (see) belong and other substances. To emergence F. various disbolism, endocrine frustration, inborn predisposition, etc. promote. Emergence F. it is caused not only hypersensitivity of skin to action of UV rays, but also to action of beams of a visible part of a solar range, at the same time existence on skin of photosensitizers is necessary.
Ability of skin to react to sunlight is more expressed during the spring and summer period.
Standard classification F. does not exist. M. A. Steinberg (1958) distinguished true (inborn and acquired) and relative photodermatoses. Treat the first solar a prurigo, or summer a prurigo (see), solar eczema (see), an actinic cheilitis (see), solar dermatitis (see), a solar small tortoiseshell (see), a solar resistant erythema (see; a pigmental xeroderma (see the Xeroderma pigmental), light smallpox (see Nuy-roa of vacciniforme), a porphyrinic disease of skin (see Porphyrias). Medicamentous photos the dermatosis including developing under the influence of cosmetics (see) and proceeding as dermatitis (see), and also professional F.
Professionalnye F., often meeting at workers of coke-chemical production (see), the aluminum industry (see), etc. concern to the second, can proceed in an easy or severe form. In conditions of production after pollution of skin and radiation by the sun there is a burning sensation, prickings, stirs under skin. Skin becomes bright red, edematous, bubbles with serous contents sometimes appear; can arise acute rhinitis (see), conjunctivitis (see), pharyngitis (see). In 7 — 10 days the erythema passes, process comes to an end with a peeling and pigmentation. A recurrence of a disease proceeds less sharply since there occurs accustoming of skin to sunshine. The diagnosis is established on the basis of the anamnesis and a wedge of a picture. Treatment provides elimination of the reasons which caused a disease, including influence of sunshine (during treatment). Appoint drugs of a quinolinic row (e.g., delagil), Bi vitamins, B12, nicotinic to - that, etc.
Prevention of aggravations F. consists in an exception of stay in the sun. Wearing hats with wide fields, points with dark glasses is recommended. Individually select the protective agents (creams, ointments, aerosols, oils) containing quinine, etc. In conditions of production for the purpose of the prevention F. use overalls, goggles (see) and photoprotective creams (see Cosmetics).
Bibliography: The multivolume guide to a dermatovenereology, under the editorship of S. T. Pavlov, t. 3, page 265, M., 1964; Steinberg M. A. Photodermatoses, M., 1958, bibliogr.; I p p e n H. Photoallergie, Therapiewoche, S. 4307, 1977.
Ya. A. Halemin.