LOBAR SCLEROSIS (Latin lobus, from grech, lobos a share; a sclerosis) — the sclerosis of a brain extending in certain sites of brain bark or on all parencephalon.
Hp develops as a result of damage of a brain in children's age at encephalitis, septic meningoentsefalita, at fibrinferments of vessels of a brain or their embolisms. Hp is observed at many genetically caused sclerosing processes of hemicerebrums. After for treatment of damages of a brain and brain vessels began to use antibiotics, steroid hormones, anticoagulants, their outcomes in Hp meet extremely seldom.
Morphologically retraction, wrinkling of atrofichny crinkles, their brownish coloring and a dense consistence is characteristic of Hp. At microscopy existence of disintegration of cells with plentiful growth of a glia is noted or total disappearance in an atrophied crinkle of nervous cells and fibers, or; from the center diversely there are regenerated fibers.
The wedge, picture depends on localization and prevalence of atrophic process. Paresis and paralyzes, disorder of coordination, a tremor, changes of reflexes, paresis of eye muscles, a nystagmus, a visual disturbance, hearing, the speech are observed, there can be epileptic seizures, dementia. In process of the course of a disease deterioration is noted by hl. obr. from mentality.
Intravital diagnosis is complicated. The diagnosis is made on the basis of a biopsy of a brain.
Prevention is directed to the prevention of the diseases causing Hp.
Bibliography D. S footer. Diseases of a nervous system at children, page 319, M., 1958; Clinical neurology, ed. by A. B. Baker, v. 1, p. 167 a.o., N. Y., 1962; Jose-p h at H. Lobare Sklerose, Handb. Neurol., hrsg. v. O. Bumke u. O. Foerster, Bd 16, S. 26, B., 1936; Oppenheim H. Lehrbuch der Nervenkrankheiten, Bd 2, S. 1334, B., 1923; S with h o p, Lobare Sklerose, Handb, spez. Path. u. Ther., hrsg. v. F. Kraus u. Th. Brugsch, Bd 10, T. 3, S. 824, B. - — Wien, 1924.
Century of B. Mikheyev.