LEPTOTRYHII of i Greek (leptos thin, thrix, trichos of hair) — bacteria of the sort Leptotrichia this. Bacteroi-daceae.
For the first time the generic name of Leptotrichia was used in 1879 by Trevisan for the description of the filamentous bacteriums living in an oral cavity of the person. L. — a limit vitel of normal microflora of an oral cavity of the person, are one of the assotsiant creating tooth plaques, belong to a conditional latogenn ym to microorganisms (see Uyel about in and about - Aage's stalemate and N ye m and kr about y).
The representative of the sort Leptotrichia — L about p to trie Iiia b and with with and 1 i s (a mustache that revsh iye
names — Leptothrix buccalis, Fuso-bacterium plauti-vincenti, Fusobacte-rhrni fiisHorme).
L. — thickened in the center, with one or two pointed ends gramotrizdatelny sticks 1 — 1,5 micron thick and 5 — 15 microns long, are often located couples, concerning each other the ends. The dispute is not formed. Cells in young cultures can be gram-positive, in old — to form the long intertwining threads with the gram-positive granules which are evenly located along an axis of threads. L. are strict anaerobes, with the content of carbon dioxide (5 — 10%) on an agar for brucellas or an agar with infusion of heart and blood well grow In anaerobic conditions and create convex, smooth, shining with rough edges («the head of a jellyfish») of colony to dia.
0,5 — 1.5 mm. After a long incubation the surface of colonies becomes gyrose and reminds a surface of cerebral hemispheres. At repeated resowings nek-ry strains gain ability to grow in conditions with the lowered oxygen content. On fluid mediums usually form a serovatobely flocculent deposit. L. ferment glucose with formation of a large number milk to - you that distinguishes them from bacteria of the sort Bacteroides and the sort Fusobacterium. An optimum of growth at t ° 37 °.
The morphology of cells of L. buccalis is similar to morphology of Fusobacterium nucleatum — the activator of ulcer and necrotic processes of an oral cavity (see Quinsy, the Spindle-shaped bacterium, Fuzobakteriya) that complicated their classification. L. buccal is unlike F. nucleatum do not form an indole, hydrogen sulfide, ammonia and carbon dioxide gas, ferment a maltose, sucrose, mannose, trehalose and salicin and especially actively glucose and fructose, hydrolyze esculin, do not reduce nitrates, have no putrefactive smell. L. buccalis is formed specific lipopolisakharid, having
properties of endotoxin. In blood serum of most of people the caption of the IgM-antibodies reacting with it lipopolisakharidy is quite high.
L. buccalis in association with other opportunistic microorganisms was allocated from contents of abscess of a jaw and piogenic granulomas; short-term bacteremia was observed after extraction of tooth. The case of development of pneumonia and sepsis, caused by L. buccalis in the patient who had a lymphoblastoid leukosis that led to a lethal outcome is known. L. buccalis. having high sakharoli-tichesky activity, perhaps, play a role in development of caries of teeth.
Bibliography: Baltrashevich A. K.
Microbes of the Bacteroidaceae family in pathology of the person and animals. Zhurn. mikr., epid. and immun., No. 10, page 14, 1979, bibliogr.; Bergey’s manual of determinative bacteriology, ed. by R. E. Buchanan a. N. E. Gibbons, p. 416, Baltimore, 1974; F i n e g about 1 d S.
M. Anserobic bacteria in human disease, N. Y., 1977; G u s t a f-s o n R. L. a. o. The biological activity of leptotrichia buccalis endotoxin, Arch, oral. Biol., v. 11, p. 1149, 1966;
M a-shimo P. A., Gen with o R. J. a. Ellison S. A. Antibodies reactive with Leptotrichia buccalis in human serum from infancy to adulthood, ibid., v. 21, p. 277, 1976; Morgen stein A. A. a. o. Serious infection with Leptotrichia buccalis, Amer. J. Med., v. 69, p.
782, 1980. T. P. Ponomareva.