KHROMOV-BORISOV Nikolay Vasilyevich

From Big Medical Encyclopedia

HROMOV-BORYSOV Nikolay Vasilyevich (sort. in 1905) — council - about a cue pharmakokhimik and the chemist-organik, the member correspondent of AMH (1961).

After the termination chemical f-that Leningrad un-that in 1930 specialized in chemistry of colorants. From 1930 to 1943 worked in Leningrad chemical and technological in-those, consistently holding positions of the assistant, research associate, acting as the department chair of colorants.

Since 1943 the manager. laboratory of synthesis of medicinal substances Leningrad chemical and pharmaceutical in-that, and since 1950 the manager. the laboratory of the same name in Ying-those experimental medicine of the USSR Academy of Medical Sciences. Since 1984 the scientific consultant in-that. In 1950 — 1975 gave a course of organic chemistry in the 1st Leningrad medical in-those. Doctor of chemical sciences (1954), professor (1955).

N. V. Khromov-Borisov is the author of the St. 150 scientific works devoted to hl. obr. to a problem of synthesis of medicinal substances, studying of communication between a structure and action of the connections possessing pharmakol. properties. Under its management and with direct participation a number of new effective medicines, including benzogek-soniya (see), methacil (see Methyluracil), pentoxyl (see), Sygethinum, was synthesized by it and it is evil (see), etc. It has more than 50 copyright certificates on inventions.

«Sign of Honour» and medals is awarded the order.

Works: Studying of a degree of activity me-

tilny group in derivatives of symmetric methyltriazine, Zhurn. general chemical, t. 30, century 6, page 1791, 1960 (sovm. from Pisareva E. V.); Derivatives of dicarboxylic acids of an imidazole, in the same place, t. 31, century 5, page 1476, 1961 (sovm. from Vinogradova N. B.); Dependence between a structure and action among structural analogs of caffeine and synthesis of antifein — medicines of a new class, Pharm. and toksikol., t. 25, century 3, page 259, 1962 (sovm. from Vinogradova N. B.); Studying of the connections a piriliya having active methyl groups, Zhurn. general chemical, t. 32, century 10, page 3211, 1962 (sovm. from Gavrilova L. A.); Sinteza and transformation of derivatives of a pyrimidine, in the same place, century 6, page 1858 (sovm. from Carleen-sky R. S.). S. V. Anichkov.