KETO-GLUTARIC ACID (synonym oxoglutaric acid) — dicarbonic (2-keto-pentadiovaya) acid is an obligatory component of the cycle of Tricarboxylic acids combining many pathways of substances (in particular, proteins, carbohydrates and fats); participates also in biosynthesis of some amino acids. In practice the wedge, biochemical, laboratories is used during the definition of activity aspartate - and alaninaminotranspherases in blood serum (see. Aminotransferases ).
Bibliography: Lenindzher A. Biochemistry, the lane with English, page 405, 522, M., 1976; Mahler G. and Kordes Yu. Fundamentals of biological chemistry, the lane with English, page 438, M., 1970; Methods of biochemistry analysis, ed. by D. Glick, v. 5, p. 107, N. Y., 1957; Methods in enzymology, ed. by S. P. Colowick a. N. O. Kaplan, v. 3, p. 404, N. Y., 1957.
B. H. Stepanenko.