HOLEGRAFIYA RADIO ISOTOPE

From Big Medical Encyclopedia

HOLEGRAFYYa of RADIO ISOTOP

NAYa (Greek chole bile + grapho to write, represent; synonym: a radiokho-legrafiya, a radionuclide holestsin-tigrafiya) — the radio isotope research of bilious ways based on fiziol. abilities of a liver to absorb from blood and to emit nek-ry hepatotropic radiofarma-tsevtichesky drugs with bile.

Several ways of a radio isotope research of bilious ways are developed (see. Bilious channels, a radio isotope research), the basic from to-rykh is the holestsin-tigrafiya. Holestsintigrafiya represents a dynamic research by means of the gamma camera (see. Radio isotope diagnostic units) of process of removal with bile of the hepatotropic radio-pharmaceutical drug including 99 t of the CU (see Radiofarmatsev-tichesky drugs). The method allows to estimate passability of bilious



Fig. 1. It is normal of Holestsintigramma, received on the gamma camera in 15, 30 and 60 minutes after intravenous administration 09 sh

the CU: the uniform image of a liver (/), accumulation

of radiopharmaceutical in a gall bladder (II), removal of this drug on bilious channels (III) in a duodenum.



Fig. 2. Holestsintigramma of the patient with not - * passability of a vesical channel in 15, 30, 45 and 60 minutes after intravenous 99 t _ _

introductions of the CU: uniform image of a liver (I); the beginning of accumulation of radiopharmaceutical in bilious channels, the image of a gall bladder is absent (And)', expanded bilious channels (III) are visible, radiopharmaceutical passes into a duodenum (IV).

channels and a biliodigestivny anastomosis to make approximate idea of situation, size and function of bilious channels and a gall bladder (fig. 1, 2), to find out passability of a vesical channel from patients with acute cholecystitis (see), to differentiate acute cholecystitis with acute pancreatitis (see), to establish the nature of jaundice (see).

The research is conducted on an empty stomach. The patient is stacked on a back and intravenously 4 — 5 mkyur (148 — 185 MBK) administer the radiofarmatsev-tichesky drug activity. Stsinti-grammy carry out in 5, 10, 15, 30, 45, 60, 90, 120 min. (if the image of a gall bladder does not appear, continue a research; in the absence of radiofarmatsevtiche-sky drug in intestines shooting is made in 24 hours). Sometimes it is difficult to distinguish the image of a gall bladder from the image of a duodenum, but usually the shadow of a bubble closely adjoins the image of a liver and unlike the image of a gut changes on the subsequent stsintig-ramma a little. To distinguish images of a gall bladder and to a dvenadtsatipa r with t of N about y guts use also slanting and side projections.

The image of a gall bladder at a stsintigrafiya appears between the 15th and 30th minute iss l edo-

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vaniye. Normal time of excretion of radio pharmaceutical drug in a duodenum — the first 2 hours, slowed down — after the 2nd hour. For studying of motive function of a gall bladder the patient is given a cholagogue breakfast.

Complications at a research are not observed.

See also Bilious channels. Bibliography: Zubovsky G. A. and

the Flint of T. V. Issledovaniye of gepatobi-liarny system by means of "t of Ts-p-bu-til-idaida, Medical radio-gramophones., t. 27, No. 1, page 28, 1982; Kasatkin Yu. N., Mironov S. P. and Mironova E. S. Stsintigrafiya of gepatobiliarny system with HIDA ~ "m of the CU, in the same place, t. 25, No. 4, page 54, 1980; Cholescintigraphy, ed. by P. H. Dried, v * 1, Hague and. lake, 1981; Hatfield P. Wise R. E. Radiology of the gallbladder and bile ducts, Baltimore, 1976; Me N u 1 t at J. G. Radiology of the liver, Philadelphia, 1977; M a t about 1 about H. N. a. lake of Value and limitations of scanning of the biliary tract, Surg. Gynec. Obstet., v. 150, p. 521, 1980; Rosenthall L. o. Diagnosis of hepatobiliary disease by "m Tc-HIDA cholescintigraphy, Radiology, v. 126, p. 467, 1978. JI. D. Lindenbraten.

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