From Big Medical Encyclopedia

HOERSCHA Alfred (Hershey Alfred Day, sort. in 1908) — the American microbiologist and the virologist, the member of National academy of Sciences of the USA, the Nobel Prize laureate (1969).

In 1930 the doctor of philosophy ended Michigan un-t, since 1934. From 1934 to 1950 professor Ying-that bacteriology at Washington un-those. Since 1950 worked in genetic department of Ying-that Carnegie, since 1962 is the head of this department.

A. Hersha's works devoted to studying of bacteriophages (see) have the greatest value. In 1952

together with Chace (M. of Chase) he published results of an experiment, to-ry showed that at development of an infection phage DNA gets inside a tank of t of e r and and l N about y cells, and the phage proteins forming a cover of a phage remain on its surface.

A. Hersha's experiences proved that genetic information of bacterial viruses is put into their DNA. To them it was also established that reproduction of a phage includes two stages: reproduction of phage DNA and synthesis of phage protein. For these researches to it together with M. Delbryuk and S. Luria the Nobel Prize is awarded.

Works: Independent functions of viral protein and nucleic acid in growth of bacteriophage, J. gen. Physiol., v. 36, p. 39, 1952 (sovm. with Chase M.); The bacteriophage lambda, N. Y., 1971 (edition, Russian lane, M., 1975).

G. B. Smirnov.