HALLISTERESIS

From Big Medical Encyclopedia

HALLISTERESIS (halisteresis; grech, hals salt + steresis deprivation) — the theory, according to a cut soft bone substance — osteoid — at nek-ry pathological processes is formed owing to decalcification of correctly created bone substance. The term «hallisteresis» is for the first time offered it. the surgeon R. Folkmann in 1865. In literature the term is used both for designation of the theory of formation of osteoid, and in its literal value — as process of extraction of lime of a bone.

Idea of G. which is the cornerstone of a softening of bones at rickets and osteomalacy was developed in works F. Recklinghausen, M. B. Schmidt, etc. A. I. Abrikosov, M. A. Skvortsov, A. V. Ryvkind were supporters of this theory also. Close to G. there is an idea of R. Lerish's ossifluence and And. The polypenalty, according to Krom a rassasyvaniye of bone structures happens by their decalcification to the subsequent dissolution of the sticking together substance and transformation of bone beams into tyazh of usual connecting fabric. In 50 — the 60th years 20 century there were representations about peritsitarny and perikanalikulyarny ossifluence (see), to-rogo expansion of bone cavities, i.e. receptacles of osteocytes and their shoots, due to lysis of adjacent bone substance results. As the theory has many opponents [G. A. Pommer, K. Shmorl, Loozer (E. Looser), A. V. Rusakov, etc.], to-rye consider that the indisputable actual data confirming G. are not received. According to these authors, lime, being an organic component of a mature bone tissue, it can be released only at dissolution of a bone as whole — its organic and inorganic parts at the same time. Results morfol, observations, pointing to emergence at nek-ry patol, states, napr, rickets, osteomalacy, on the periphery of bone structures (bone beams, walls of gaversovy canals, subperiosteal sites of a bone) of the zones of ossiform fabric which are brightly painted a carmine (carminic zones) are the basis for idea of G. Consider that these zones arise in connection with decalcification of a bone; further decalcification can extend to all bone beam, osteon, an inserted plate.

According to F. Reklingkhauzen, after decalcification there is a raspravleniye of agglutinant of a bone to identification of its collagenic basis and formation of so-called figures of the lattices which are well found during the processing of cuts of not decalcified bone by weak acids during the coloring by thionine. «Figures of lattices» are noted on border of calciphied and not calciphied parts of a bone, where as assume, the amount of limy salts is sharply reduced. However G. referred as the proof morfol, pictures can be interpreted as a result of a new growth of ossiform fabric, edges remains not calciphied.

The possibility of intravital extraction of limy salts from a bone at safety of its organic part is based on the wrong idea of adjournment of lime in a bone as about the process submitting only physical. - to chemical patterns. Actually it is very difficult biol, process, at Krom is carried out strong organic communication of limy salts and a protein basis of a bone. Amount of mineral substances in a mature bone — a constant. Therefore change of this size, and also change in the structure of a bone tissue are possible only in the course of its new growth. A. V. Rusakov's researches showed that at rickets and osteomalacy ossiform fabric contains less osteocytes, and the arrangement of bone beams and their quantity differ from norm markedly that is the indisputable certificate of a new growth of ossiform fabric, but not its emergence owing to decalcification of a mature bone. Open And. V. Rusakov the type of a rassasyvaniye of a bone tissue called «an alar rassasyvaniye» also contradicts G.

See also Osteomalacy , Rickets .

A. V. Smolyannikov.

Яндекс.Метрика