From Big Medical Encyclopedia

FUZOBAKTYoRII — rhabdoid bacteria of the sort Fusobacterium this. Bacteroidaceae.

T. live on mucous membranes of an oral cavity and intestines of the person and animals. They treat opportunistic microbes (see), to-rye participate in development of purulent and necrotic processes. The name of the sort Fusobacterium (a spindle-shaped stick) is given in 1922 to Knorrom (M. by Knorr) without indication of type-species. Since 1974 type-species consider F. nucleatum.

T. — obligatno the anaerobic gram-negative sticks which are not forming a dispute. By the size, in separate culture bacteria of a type of F. nucleatum. F. necrophorum have a typiform of the thin spindle-shaped sticks identical and fuzobak-teriya of other types represent polymorphic sticks with the rounded-off or slightly pointed ends of various length, from almost kokkovidny forms to threads 10 microns long. Cells of nek-ry types F. can have thickenings or form free round bodies (sferula). T. happen motionless or mobile (to peritri-hialny flagellums). They are easily painted by aniline dyes, in cells of separate types grains (granule) are painted over.

T. — the heterotrophic organisms which are well growing on blood dense mediums and on fluid mediums with a tryptic repitch of casein and Hottinger's repitch (see Mediums). On Wednesdays usually add a yeastrel and cysteine. Blood serum, ascitic liquid, starch, glucose and carbon dioxide gas stimulate their growth. T. grow in the presence of gentsia-new violet and other dyes that is used in the selection environments (see). at F. varium and F. mortiferum ir addition of bile grow. On fluid mediums F. form granular, cotton or slimy precipitate. Cultures have a putrefactive smell. T. metabolize peptones, and also carbohydrates with weak decrease in pH of the environment in the acid party, a staple of fermentation is oil to - that. Nek-ry types F. hydrolyze esculin. form an indole, slowly liquefy to gelatin, changeably reduce nitrates. F. necrophorum splits bilious to - you. At F. nucleatum and

F. necrophorum heterogeneity on antigenic properties is revealed whether-popolisakharidy their cell walls are endotoxins. F. the dog-rophorum forms exotoxin with thermostable leykotsidalny and with thermolabile hemolitic activity.

T. can be found at tonsillitis, pneumonia, abscesses of a lung, liver and other pyoinflammatory processes. Despite sensitivity to many antibiotics, they can cause heavy sepsis (see) with the phenomena of a septicopyemia. Most often in patol. the centers find F. nucleatum and F. necrophorum (see the Necrobacillosis).

At parenteral infection; mice and rabbits of F. necrophorum and F. mortiferum the disease leading to death of animals develops. F. nucleatum shows weak pathogenicity in pure growth.

At infection in the mixed culture a synergism of the accompanying microbes increases pathogenic action of F. nucleatum.

Constant combinations in patol are known. material F. and other bacteria:

F. nucleatum and spirochetes at Simanovsky's quinsy — Plauta — Vincent (see Quinsy), F. nucleatum and Ba-cte-roides nodosus at hoofed decay of sheep.

Bibliography: B and l of t r and sh e in and the p A. K.

Mikroby of the Bacteroidaceae family in pathology of the person and animals, Zhurn. mikr., epid. and immun., LM 10, page 14, 1979; Bergey’s manual of determinative bacteriology, ed. by R. E. Buchanan a. N. E. Gibbons, Baltimore, 1975. A. K. Baltrashevich