From Big Medical Encyclopedia

FOOD CENTER — the complex of functionally interconnected structures of the central nervous system regulating a feeding behavior and coordinating activity of a digestive tract.

According to I. P. Pavlov's ideas of nerve centers (see. Centers of a nervous system ) Item of c. provides the mental, sensitive and motive processes connected with the act of food and digestion of food including secretory function of glands of a digestive tract, and also motor acts (chewing, swallowing, further transportation of a food lump, etc.).

The important role in emergence of various subjective states connected with development of a purposeful feeding behavior belongs to kernels of a hypothalamus (see. Hypothalamus ) and to their influence on other structures of c. N of page. It is experimentally established that in lateral kernels of a hypothalamus there is a center of food, and in ventromedialny — the center of saturation. In formation food motivations (see) — bases of a purposeful feeding behavior, in addition to lateral kernels of a hypothalamus, participate various educations limbic system (see), reticular formation (see) a brainstem and cerebral cortex (see). To P. of c. also groups of cells in different departments of c belong. the N of page sending efferent impulses to the executive bodies, glands and muscles participating in digestion (see).

The important role of adreno-sensitive formations of a hypothalamus and limbic system in development of a feeding behavior is established. In animal experiments it is shown that introduction of adrenomimetik (noradrenaline and adrenaline) directly in a hypothalamus through the cannulas implanted in a brain was followed by increase in consumption of food both full, and hungry animals; injections of adrenoblockers — decrease in consumption of food.

P.'s excitability of c. depends on receipt of nervous impulses from the periphery from various receptors, including receptors of a digestive tract, and also from composition of blood, in particular concentration of glucose, some amino acids, oligopeptid, free fat to - t and a number of hormones, napr, insulin. The important role of many environmental factors in maintenance of a functional condition of P. of c is proved.

Bibliography: Anokhin P. K. and Sudakov K. V. Neurophysiological theory of hunger, appetite and saturation, Usp. fiziol. sciences, t. 2, No. 1, page 3, 1971, bibliogr.; Pavlov I. P. Complete works, t. 2, book 2, M. — L., 1951, t. 6, page 148, 1952; System mechanisms of motivation, under the editorship of K. V. Sudakov, M., 1979; K. V Pike perches. Biological motivations, M., 1971; Physiology of digestion, under the editorship of A. V. Solovyov, etc., L., 1974; Sh at - leukin K. B. System organization of a feeding behavior, M., 1971, bibliogr.; A n a n d B. To. Regulation of nervous drives in feeding behavior, Totus homo, v. 3, p. 59, 1971, bibliogr.; O o m u r a Y. Central mechanism of feeding, Advanc. Biophys., v.5, p. 65, 1973, bibliogr.

V. G. Zilov.