From Big Medical Encyclopedia

FASTsIOLOPSIDOZ (fasciolopsi-dosis) — the helminthosis of the person and animals which is characterized by a chronic current with preferential damage of a stomach and intestines, development in a late stage of a disease of dystrophy of a liver and a cachexia.

Activator F. for the first time found Busk (Busk, 1843), described Lancaster (Lankaster, 1857); the biology of a parasite is studied by Nakagawa (To. Na-kagawa, 1921). T. it is eurysynusic in a number of districts of Central and Southern China, Bangladesh, India, in Burma, Thailand, Kampuchea, Laos, Vietnam, on the Philippine

islands. In the USSR infection F. it is not registered. In 1937. To. y. Scriabin for the first time described the brought in case of a fastsiolo-psidoz revealed in the USSR.

Activator F. — a trematode of Fas-ciolopsis buski (Lankaster, 1857), Stiles, 1901 (a synonym of Fasciolopsis fulle-borni Rodenwalt, 1909) from the Fasciolidae Railliet family, 1895. The trematode has red-orange color, the yazykovidny form, length of 15 — 50 mm, width of 8,5 — 20 mm. Eggs oval 0,13 in size — 0,14 X X 0,08 — 0,095 mm. Adult Tpeivia-toda parasitizes in a small bowel, a stomach, sometimes in a liver, a pancreas of the person, dogs, pigs, boars, cats who are final owners. Together with excrements of egg are allocated to the environment; the eggs which got to water in

2 — 3 weeks leave a larva — miratsi-diya, edges gets into a body of the intermediate owner — a mollusk of the sort Planorbis and nek-ry others where there takes place the asexual reproduction of helminth with change of a lineage which is coming to an end with formation of larvae having a tail — cercariae. The last leave in water, are attached to stalks or tubers of plants and intsistirutsya, turning into invasive larvae — and to the wood of a hickory. Development and maturing of a parasite in water happens within 90 — 95 days. Get to an organism of the final owner of an adolescaria with edible water plants or water.

Sources of an invasion are patients F. person and animals. Major factors of transfer F. — water of open reservoirs and water nuts (Trapa natans), to-rye people quite often clear of a peel teeth.

stalks and leaves of a lotus, tubers of water plants of Eleocharis tuberosa and Spirodela polyrhysa.

Metabolites of larval and mature forms of helminth make toksiko-allergic impact on an organism with development of inflammatory process and ulcers in a mucous membrane went. - kish. path. It leads to disturbance of absorption in intestines, dystrophy of a liver that promotes development of a hypoproteinemia (see the Proteinemia), hypostases (see Hypostasis).

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extensive cankers of a stomach, thin, and sometimes and a large intestine, a hyperemia of bodies, hemorrhages, proteinaceous and fatty dystrophy of a liver (see the Liver, pathological anatomy).

Distinguish early and chronic phases of a current of F. V to an early phase abdominal pains, by times of an excrement liquid fetid, to

5 — 6 times a day are noted (see Ponosa). In hron. to a phase depending on weight F. proceeds or with moderate abdominal pains and periodic frustration of a chair, or in the form of heavy intestinal crises (see Intestines, diseases), persistent ponos with liquid excrements without impurity of blood, from the remains of undigested food that brings in a result to a cachexia (see). The last proceeds in an edematous form with ascites, an anasarca or in a dry form — with a hypothermia, arterial hypotension, a hypoproteinemia of extreme degree, anemia and can end letalnsh with an outcome.

The diagnosis the wedge, pictures, detection in excrements of eggs, and sometimes establish on the basis mature parasites. The differential diagnosis is carried out with hron. intestinal infections and invasions, a strongyloidosis (see), to a spr (see).

Treatment is carried out by Naftamonum and a prazikvantel.

The forecast — favorable if treatment is carried out in an early phase, and heavy in the started cases.

Prevention — planned mass treatment of people and animals; protection of reservoirs from pollution by their excrements; boiling of the water from open reservoirs used for drink and economic needs, heat treatment of the water plants eaten.

See also Trematodoza.

Bibliography: Gelminto; sh the person,

under the editorship of F. F. Soprunov, M., 1985; The Guide to tropical diseases, under the editorship of

A. Ya. Lysenko, M., 1983; Tropical

diseases, under the editorship of E. P. Shuvalova, M., 1979. H. N. Ozeretskovskaya.