From Big Medical Encyclopedia

ERYTHEMA INFECTIOUS (erythema infectiosum; Greek erythema redness + poses day of armor. infectio infection; a synonym the fifth disease) — the infectious disease which is characterized by spotty and papular rash and absence or weak expressiveness of the general intoxication.

A. Tschamer is for the first time described in 1886. Nek-ry researchers called in question existence E. and. as independent nosological form also identified it with the ESNO-dieback (see. Enteroviral diseases). In 1959 Alexander (M. of Alexander) showed that an erythema infectious and the ESNO-dieback differ on a nek-eye a wedge, and epidemiol. to signs are also different diseases.

The etiology and a pathogeny are not known. The virus nature of a disease is supposed. Infection, apparently, occurs in the airborne way. A susceptibility to E. and. low. Children of 5 — 12 years are ill preferential, is much more rare — adults. AA. and. meets in the form of sporadic cases and small flashes in families and child care facilities. After the postponed disease there is a durable immunity.

The pathological anatomy is not studied.

The incubation interval usually proceeds 4 — 14 days. The main symptom is rash, edges at first develops on cheeks and a ridge of the nose in the form of the small red spotty and papular educations, at merge forming an erythema in the form of a butterfly. For the 2nd day of a disease of a rash extend to extremities, lokalizuyas it is preferential on their extensor surfaces. Elements of rash, quickly increasing in a size, merge in the centers of irregular shape, to-rye begin to turn pale from the center and get grayish and cyanotic coloring, forming a peculiar setevidny drawing on skin. The peeling is not observed. Rashes can be followed by short-term subfebrile condition. The hyperemia of a pharynx, increase limf, nodes are possible. In blood the leukopenia, band shift to the left, the eosinophilia accelerated by ROE is found. At a severe disease, a cut it is sometimes observed at adults, high temperature, significant increase limf, nodes, neuralgia, an arthralgia is noted.

The diagnosis is made on the basis by a wedge, pictures. The differential diagnosis is carried out with measles (see), a rubella (see), the ESNO-dieback. The prodromal stage, the expressed catarral phenomena and Velsky's spots — Filatova — the Cop face, absence of an eosinophilia are characteristic of measles. At a rubella pour less bright, melkopyatnisty, its elements have no tendency to merge; the expressed swelling of occipital lymph nodes is noted. The ESNO-ekzan-tema more kontagiozn, is often observed at adults, characterized by variability of rash, more expressed phenomena of intoxication, and sometimes and other displays of an enteroviral infection.

Symptomatic treatment.

Forecast favorable.

Prevention is not developed.

Bibliography: Bryukhanova L. K. and d river. An infectious erythema of Tshamer at children, Pediatrics, J4» 7, page 52, 1976; Bystryakova L. V. Infectious a dieback at children, L., 1982; The Willow

A. I is new. Infectious diseases from ekzantema, page 133, L., 1970;

nke W. Klinik des einheimischen Infektionkrankheiten, S. 90, Lpz., 1962; Krugman S. Katz S. L. Infectious diseases of children, St Louis a. o., 1981; Trub C. L. P. u. Posch J. Die Erythema infectiosum

(Exanthema infectiosum variabile) — Pandemie 1958, Med. Mschr., S. 149, 1960; T s with

h a-m e r A. Ueber ortliche Rotheln, Jb. Kin-derheilk., Bd 29, S. 372, 1889.

S. D. Nosov.