From Big Medical Encyclopedia

EMBDEN Gustav (Embden Gustav, 1874 — 1933) — the German biochemist.

In 1899 — 1903 worked in F. Hofmeister laboratory. Since 1904 managed clinical laboratory (since 1907. Physicochemical institute) in Frankfurt am Main. In 1907 it was chosen privat - the associate professor, in 1909 — extraordinary professor, and in 1914 — ordinary professor and the department chair of biological chemistry Frankfurt un-that.

G. Embden's works are devoted to researches in the field of an intermediate metabolism of carbohydrates, fats and proteins. He studied education milk to - you and a number of intermediate products at glycolysis, sugars from amino acids and trioses in a liver, a role of a liver in synthesis of amino acids from keto-, oxyacids and ammonium salts, sources of emergence of acetone bodies in an organism. G. Embden made a big contribution to chemistry of muscular contraction: are allocated to them hexosemonophosphoric and adenosinephosphoric (adenylic) to - you, the role milk to - you and phosphorus in the course of muscular contraction is established. In 1933 he offered the new scheme of anaerobic zymolysis of carbohydrates, according to a cut, the way to end products lies not through methyl glyoxal as considered earlier, and through three-carbon fosforilirovanny products — phosphotrioses, phosphoglyceric and pyroracemic to - you. The scheme offered by G. Embden was of great importance in development of modern ideas of ways of disintegration of carbohydrates at glycolysis (see) and fermentation (see).

Works: Eine gravimetrische Bestimmungs-Methode fur kleine Phosphorsauremengen, Handb. biol. Arbeitsmeth., hrsg. v. E. Abderhalden, Abt. 1, T. 3, S. 913, B. — Wien, 1921; Nachweis, Bestimmung und Isollerung von Azeton, Azetessigsciure und Oxybuttersaure, ibid., Abt. 4, T. 5, Hft.l, S. 187, P. — Wien, 1931 (sovm. with Schmitz E.); t)bcr die intermediaren Vor-gange bei der Glykolyse in der Muskulatur, Klin. Wschr., S. 213, 1933 (sovm. with other); Tatigkeitssubstanzcn der quergestreiften Muskulatur, Handb. biol. Arbeitsmeth., hrsg. v. E. Abderhalden, Abt. 5, T. 5-A, S. 1590, B. — Wien, 1936.

Bibliography: Deut_cke. Gustav Embden, Ergebn. Physiol., Bd 35, S. 32, 1933, Bibliogr.; Lennartz E. Gustav Embden, Med. Welt (Berl.), S. 1231, 1933.