From Big Medical Encyclopedia

DESOXYRIBOSE (2 desoxyribose; With 5 H 10 O 4 ) — the connection representing a D-ribose in a molecule a cut the hydroxylic group at the second carbon atom is replaced with hydrogen; is the only typical carbohydrate component of deoxyribonucleic acid — carriers of hereditary properties of all live organisms. Constitutional formula:

In molecule DNA is in a furanozny form, its first carbon atom is connected with purine (or pirimidinovy) the basis, and the fifth and third carbon atoms form radio communication with the remains phosphoric to - you, connecting deoxyribonucleotides in a chain of DNA polymer. Thus, a basis of polymeric molecule DNA is poli-2-dezoksi-D - ribozo-3,5' - a phosphatic chain.

Represents colourless crystals, well water soluble and alcohol, t ° pl 78 — 82 °; [a] D from — 91 ° to — 58 ° (in water). Both in a free look, and as a part of DNA gives a number of specific staining reactions, napr, with Schiff's reactant — Feylgen's reaction, with diphenylamine — Dishe's reaction (see. Dishe method ), staining reaction with cysteine and a chamois to - that, etc. Methods of quantitative definition of DNA in cells and tissues of animals, plants and in microorganisms are based on these reactions.

D.'s education in an organism happens at the level of nucleotides. In the course of biosynthesis of deoxyribonucleotides D.'s rest is formed at recovery of a ribotsitidindifosfat (TsDF) in dezoksiribotsitidindifosfat (dTsDF) at the expense of sulphhydryl (SH) groups of a tioredoksin or lipoic to - you in the presence of NADF-N, ATP and ions of Mg 2+ . D.'s biosynthesis by enzymatic condensation plays, apparently, a supporting role.

See also Deoxyribonucleic acid , Nucleic acids , Ribose .

Bibliography: Debov S. S. Exchange of nucleic acids, in book: Chemistry and biochemistry of nucleic acids, under the editorship of I. B. Zbarsky and S. S. Debov, page 121, L., 1968; Chemistry of carbohydrates, under the editorship of N. K. Kochetkov, etc., M., 1967; The nucleic acids, ed. by E. Chargaff a. J. N. Davidson, y. 1, N. Y., 1955, bibliogr.

A. H. Belozersk, I. B. Zbarsky.