DESMOID

From Big Medical Encyclopedia

DESMOID (Greek desmos communication, sheaf + eidos look; synonym: desmoidny fibroma, desmoidny tumor, fibrosarcoma, musculoaponeurotic fibromatosis) — a connective tissue new growth from group of fibromatoses; treats processes, boundary with tumoral. The term was offered by J. Macfarlane in 1832 and is applied to the tumors proceeding preferential from a tendinous vagina of a direct muscle of a stomach, sometimes from the fascial device of muscles of a back, a thorax, and also top and bottom extremities.

The origin of D. remains obscure though recognized etiol, the moment is: injury.

Microscopic picture of desmsidny fibroma: the intertwining connective tissue fibers (1), small vessels (2), fibroblasts are expressed (3).

Macroscopically D. represents very dense, usually single node, on a section of a fibrous look, grayish-yellow color, unsharply delimited from surrounding fabrics. At microscopy (fig.) the node consists of the intertwining bunches of the collagenic fibers which do not have a certain orientation and mature fibroblasts and fibrocytes. Mitoses are extremely rare. In peripheral departments of D. infiltration of surrounding fabrics elements of a new growth sometimes is found. Depending on quantity of cells and tendency they to proliferation are allocated by fibromatous and sarkomatozny types D. The last is close to to a fibrosarcoma (see), from a cut it is difficult to distinguish it. In D. the centers of sliming are possible. Such tumors have more expressed invasive properties and in rare instances can give metastasises.

Distinguish abdominal and ekstraabdominalny. They meet seldom, making 0,03 — 0,16% of number of all new growths. Can arise at any age, but a thicket in 25 — 35 years, especially at the giving birth women. D. slowly grows, without causing usually any painful symptoms though sometimes after all is followed by pains. In the started cases can sprout skin and ulcerate, burgeon through an abdominal wall in abdominal organs, cause an atrophy of muscles, and at an ekstraabdominalny arrangement — to grow into large blood vessels, nerves and bones.

The diagnosis is based on set a wedge, and morfol, data. The only method of treatment of D. is their broad excision within a fascial and muscular case of the affected muscle. The forecast of a disease not always favorable since the malignancy is possible.

A recurrence is frequent.

See also Fibroma, fibromatosis .


Bibliography Vikhert And, M., Galil Oglou G. A. and Poroshin K. A. Tumors of soft tissues, page 63, M., 1969, bibliogr.; Malignant tumors, under the editorship of H. N. Petrova, page 265, L. — M, 1934; Clinical oncology, under the editorship of H. N. Blochina and B. E. Peterson, t. 1, page 223, M., 1971; About l x about in with to and I am I. G. and To and-z and N of c of e in and I. A. Desmoidnye of a tumor and their mitotic mode (morphological diagnosis and questions of forecasting), Arkh. patol., t. 38, No. 11, page 39, 1976; A. I. Cancers and Chekharina E. A. Malignant tumors of soft tissues of extremities and trunk, page 75, L., 1968, bibliogr.

H. N. Trapeznikov.

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