DAUCARINUM (Daucarinum) — antispasmodic; the purified drug from seeds of Daucus carota or Daucus sativus carrots (Hoffm.) Rochl. families of umbrella (Umbelliferae). Contains derivatives of coumarin (umbelliferone, esculetin, skopoletin, ostol, etc.), flavonoids, amine and fenilkarbonovy to - you.
— with a specific smell, we will poorly dissolve yellow-brown amorphous powder of bitter taste in water, we will dissolve in 50% alcohol. On pharmakol, drug is close to action to to kelline (see). Under the influence of D. at most of patients with hron, coronary insufficiency urezhatsya attacks of stenocardia and their intensity decreases. On a nek-eye to data, D. has positive effect at the arrhythmias caused by coronary insufficiency. Increases the vital capacity of lungs and reduces a bronchospasm.
Apply D. to treatment hron, coronary insufficiency. Appoint inside 0,02 g of 3 — 5 times a day in 30 min. prior to food. Course of treatment of 2 — 4 weeks. The therapeutic effect occurs in 3 — 5 days after an initiation of treatment.
Is well transferred by patients and usually does not cause side effects or allergic reactions that allows to appoint drug on an outpatient basis.
Form of release: tablets on 0,02 g. Keep in the cool, protected from light place.
See also Antispasmodics .
Bibliography: Ya. I. and Cherkasov I. N. hajjs. About normal distribution of the sizes characterizing coronarodilator effect of Daucarinum and anetin in book: Pharm, and toksikol., under the editorship of F. P. Trinus, century 5, page 34, Kiev, 1970.
Ya. I. Hadzhay.