CHERNUH Alexey Mikhaylovich (1916 — 1982) is the Soviet pathophysiologist, the academician of AMH (1971), the vice-president of AMH (1974—1982), the winner of the State award USSR (1977). The member of the CPSU since 1948.
In 1938 Leningrad medical in-t ended the 2nd (nowadays Leningrad a sanita rno-hygienic
medical in-t), worked as the research associate at the Urovsky research station in the Chita region. In 1939 — 1941 the graduate student of VIEM in Moscow. From 1941 to 1945 would manage a neurology unit in Novokuznetsk. In 1945 — 1954 the research associate, the scientific secretary, the deputy director by a scientific part Ying-that the general
and experimental pathology of the USSR Academy of Medical Sciences. In 1954 — 1957 the deputy director Ying-that normal and pathological physiology of the USSR Academy of Medical Sciences. In 1955 protected dokt. the thesis on the subject «Nervous Irritation in the course of an Inflammation»; professor (1958). In 1957 — 1965 the manager worked. department of chemotherapy Ying-that pharmacology and chemotherapy of the USSR Academy of Medical Sciences (nowadays Ying t of pharmacology of the USSR Academy of Medical Sciences). Since 1965 the director Ying-that normal and pathological physiology of the USSR Academy of Medical Sciences, and after his reorganization in 1974 until the end of life was a director Ying-that the general pathology and pathological physiology of the USSR Academy of Medical Sciences.
A. M. Chernukh is the author of St. 300 scientific works, including 5 monographs. It one of initiators and direct participants of development of a problem of microcirculation. A. M. Chernukh offered original methods of an intravital research of microvessels that allowed to obtain essentially new data on structure and function of a microcirculator bed (see Mikrotsirkulyation). Researches A. M. Chernukh and the collective headed by it made essential changes to ideas of an innervation of microvessels. The bessinaptichesky type of an innervation was found, the possibility of reduction of endothelial cells and change of vascular permeability under the influence of vasoactive substances (histamine) is shown; the concept of «a functional element the» of body which is a structural and physiological basis of interface of blood supply, an innervation and metabolism is offered.
In the works devoted to a pathogeny of an inflammation they were given an all-biological assessment of reaction of an organism to damage and the principles of rational pathogenetic therapy are experimentally proved. In its works the analysis of mechanisms of a disease and recovery, and also questions of methodology of the general pathology and the doctrine about a disease figures prominently.
award USSR A. To M. Chernukh it was awarded for a cycle of the works on studying of microcirculation published in
1967 — 1975. In 1978 among authors of the work «60 years of the Soviet health care» it was conferred an award of the USSR Academy of Medical Sciences of N. A. Semashko.
A. M. Chernukh was the vice-president of the USSR Academy of Medical Sciences, the chairman Vsesoyuznogo about-va pathophysiologists (1967 — 1982); the chairman of the board of science medical foundations M3 of the USSR (1970 — 1972), the member of the Advisory board on medical researches at WHO, the deputy chairman Vsesoyuzny of society «Znaniye», the member scientific medical about-in Italy, the USA, ChSSR, and also the member of some other Soviet and foreign scientific about - century. It is awarded honourable medals of R. Virkhov (GDR), I. Zemmeljveys (VNR), G. Selye (it is founded in ChSSR), Ya. Purkinye (ChSSR).
A. M. Chernukh was a member of editorial board and the deputy editor-in-chief of a redotdel «Pathological physiology» of BME.
It is awarded by the Order of Lenin, an award of the Labour Red Banner, the award «Sign of Honour» and medals.
Works: Nervous irritation in the course of an inflammation, a yew., M., 1955; Antibiotics
of group of tetracyclines, M., 1962 (sovm.
with Kivman G. Ya.); Infectious center of an inflammation, M., 1965; About teratogenic
effect of chemical (medicinal) substances, M., 1969 (sovm. with Alexandrov P. N.); Microcirculation, M., 1975 (sovm. with other); Inflammation, M., 1979.
Bibliography: Urgent problems of the general pathology and a pathophysiology,
page 3, M., Is devoted 1976 to the 60 anniversary of the academician of the USSR Academy of Medical Sciences A. M. Chernukh, under the editorship of A. D. Ado and A. M. Sovetov; To e m and-leva 3. Academician Alexey Mikhaylovich Chetenukh, Eksp. medical morfol., t. 21, No. 4, page 203, 1982. P. N. Alexandrov.