From Big Medical Encyclopedia

CAROTENEMIA (carotene + Greek haima blood) — the excess concentration in blood of carotinoids causing coloring of plasma and certain sites of skin in yellow color. Coloring appears at the maintenance of carotinoids in plasma higher than 400 mkg in 100 ml (norm 80 — 230).

To. quite often arises at healthy people, especially at children of younger age who eat many vegetables and the fruit containing carotinoids (oranges, tangerines, carrots and juice from them). The yellow coloring of skin appearing at the same time carries the name a carotene hyperchromia of skin (a synonym: aurantiaz skin, yellow disease, carotinosis, xanthodermia, xanthosis, okhrodermatoz, pseudoicterus). For the first time the carotene hyperchromia of skin under the name aurantiaz skin is described by E. Baelz in 1896 as result of excessive consumption of oranges. At an aurantiaza of skin carotinoids are deposited in epidermis. Skin of palms, soles of feet, lobes of ears, sometimes all body is most often painted. As a rule, scleras and mucous membranes are not painted that is considered at differential diagnosis with jaundice (see). The carotene hyperchromia of skin gradually disappears at the terminations of the use of the products containing carotinoids.

The carotenemia is observed at acute damages of a liver, a diabetes mellitus (a diabetic xanthosis), hron, a glomerulonephritis with a renal failure, a myxedema, and at children as well at dystrophies. According to a number of researchers, emergence To. at these diseases it is caused by decline in the ability of a liver to turn arriving with food carotinoids (see) in vitamin A therefore there is their accumulation in blood and fabrics. For emergence To. the lipidemia which is quite often accompanying these diseases matters. At these diseases of special treatment To. it is not required; therapy of a basic disease is carried out.

N. G. Zernov.