From Big Medical Encyclopedia
Argyrophil fibers in marrow (according to Maximov): 1 — a venous sine; 2 — an endothelium; 3 — reticular macrophages; 4 — argyrophil fibers; 5 — myeloid fabric; 6 — lipoblasts; 7 — a megacaryocyte.

ARGYROPHIL FIBRES (synonym: reticulin, trellised, prekollagenovy, argentofilny) — one of types of fibrous formations of connecting fabric. And. come to light in tissue specimens after the special processing (fixing of objects in formalin, processing of cuts in solutions of silver nitrate in various modifications — see Argirofilnost) promoting coloring (impregnation) of fibers metal silver century; in the term property A is noted. to contact the metal silver which is dropping out in the form of a black deposit of solution of its nitrate salt century. And. are described by K. W. Kupffer in 1876 century. On tissue specimens And. come to light after silvering in the form of network of the thin branching fibrils between cellular components century (their name «trellised fibres», meeting in a liver, kidneys, adrenal glands from here). In the hemopoietic bodies And. cover walls of endothelial sine century, and also make a framework, on Krom reticular macrophages (fig.) are located. And. form dense network in the centers of follicles limf, nodes and a spleen century. Substance, from to-rogo consist And. century, differs from collagen and elastin in resistance to effect of weak acids and alkalis, and also to peptic and tryptic digestion in this connection it during a classical era of histology was characterized by the special term «reticuline» though its chemical nature was not deciphered. And. give the positive PAS-reaction testimonial of existence of a polisakharidny component century. Origin And. century is studied insufficiently. Assume that producers A.v. reticular macrophages among which are found are And. century. However in an embryogenesis And. appear among the mezenkhimny cells which are not finding a noticeable differentiation on histoid and fibroblastichesky elements century. Elektronnomikroskopichesky researches did not give the final answer to a question of relationship of reticuline and collagen yet. In the embryonal bodies containing And. century, napr, a liver, all reticulin stroma has an appearance of the amorphous substance with a weak electron density deprived of fibrous components like elementary collagenic protofibrils with characteristic (64 nanometers) frequency. This substance, apparently, is produced by reticular (kupferovsky) macrophages. Similarity of substance A is emphasized. century in electronic microphotos with substance of basal membranes (see. Basal membrane ). Some authors nevertheless point to basic similarity of substance A. century and collagen (see). Plentiful development And. it is characteristic of a number of productive inflammatory processes, napr, at development of tubercular granulations century. Many pathological changes of bodies are followed by swelling, lysis, and also calcification And. century.

Bibliography: Histology, under the editorship of. In, G. Yeliseyev, page 158, M., 1963; Maximov A. A. Fundamentals of histology, p. 2, Pg., 1918; Polikar A.ikolle A. Physiology of normal and pathological connecting fabric, the lane with fr., Novosibirsk, 1966; Romey with B. Mikroskopicheskaya of the technician, the lane with it., M., 1954; Jackson D. S. and. Steven F. S. Some biochemical considerations of connective tissue proteins in disease, in book: Biol, basis med., ed. by E. E. Bittar a. N. Bit-tar, v. 3, p. 249, N. Ύ. — L., 1969, bibliogr.; Jackson S. F. Connective tissue cells, in book: Cell, ed. by J. Brachet a. A. E. Mirsky, v. 6, p. 387, N. Ύ., 1964; Porter K.R.a.Bonneville M. A. An introduction to the fine structure of tissues, Philadelphia, 1964.

A. H. Studitsky.