From Big Medical Encyclopedia

ANISOCORIA (anisocoria; Greek anisos — unequal and kore — a pupil) — inequality of diameters of pupils caused by disturbance of ways of a pupillary reflex (unilateral or bilateral) or their kernels and in this regard — disorder of interaction of muscles of an iris of the eye. The muscle narrowing a pupil nnnervirutsya by parasympathetic fibers of a third cranial nerve: the muscle expanding a pupil — the sympathetic fibers (from a texture of an internal carotid artery) concerning the relevant spinal center. At digging in in a conjunctiva of eyes of solutions of Pilocarpinum, atropine and cocaine, previously having measured diameters of pupils, it is possible to establish the party of defeat of a pupillary innervation more or less precisely.

The ANISOCORIA meets at various damages of the central nervous system (tumors of a brainstem, injuries of a skull, a myelosyringosis, epidemic encephalitis, etc.), is more often at a neyrolyuesa. Some diseases of internals, in particular lungs, can also lead to expansion or narrowing of one of pupils owing to reflex impact on sympathetic bunches of nerves of the relevant party.

The ANISOCORIA is observed at various disturbances of ways of a parasympathetic or sympathetic innervation of a pupil, and also the afferent pupillary ways passing in an optic nerve. If pharmacological tests do not exert impact on the ANISOCORIA, it is necessary to consider that it arose owing to damage of an optic nerve.

See also Pupillary reflexes .

Bibliography: The multivolume guide to eye diseases, under the editorship of V. N. Arkhangelsky, t. 1, book 1, M., 1962; Tronas E. Zh. Glaz and neurosurgical pathology, page 114, L., 1966; Der Augenarzt, hrsg. v. To. Velhagen, Bd 2, S. 460, Lpz., 1959, Bibliogr.

V. A. Smirnov.