From Big Medical Encyclopedia

AKROPIGMENTATION symmetric (acropigmentatio symnietrica; Greek akron — an extremity, lat. pigmentum — coloring) — the hereditary dermatosis which is characterized by a hyperpegmentation preferential of skin of extremities. Are known: And. symmetric Doha — Komaya, And. reticular Kitamura, And. hyponychial Tureya, hereditary symmetric diskhromatoz Toyama, akrodiskhromatoz Matsumoto — Komaya — Toyama.

On the extensive parties of distal departments of extremities, is more rare on a neck, a face, a crotch, there are plentiful, different shades brown spots which are often merging, sometimes forming a close-meshed grid. Subjective feelings usually are absent. And. it can be combined with other inborn defects, e.g. mentally retarded, vasodilatation of a retina (a syndrome of Doha).

Histopathology — a moderate hyperkeratosis, thinning of epidermis, shortening of interpapillary shoots, in which tops of adjournment of a pigment.

The differential diagnosis is carried out with the pigmental xeroderma differing in polymorphism of rashes and hypersensitivity to sunshine with lentigo, elements to-rogo are slightly raised. Current long.

Treatment And. the bleaching and peeling means gives unstable effect. Treatment of a syndrome of Doha — symptomatic. See also Genodermatoses .

N. A. Torsuyev.