ACETOACETIC ACID (C 4 H 6 O 3 ) — organic compound from group of beta ketonic acids; one of components of acetone bodies; intermediate product of exchange of amino acids and fatty acids.
And. to. represents dense liquid, well water soluble, alcohol and ether. In aqueous solutions decays at weak heating on acetone and carbon dioxide gas. It is formed in an organism as an intermediate product of exchange of fatty acids and amino acids: leucine, phenylalanine, tyrosine, etc. Quantity And. to. in blood of 0,3 — 2 mg of %, in urine — 3 — 15 mg per day. Contents And. to. in blood and urine increases at disturbances carbohydrate metabolism (see), and also at starvation, acute feverish processes (is more often at children), etc. Especially considerably (to 6 g, and sometimes and more in daily urine) allocation And. to. at severe forms of a diabetes mellitus. Administration of carbohydrates and insulin lowers contents And. to.
See also Ketone bodies .